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Living Modified Organism
(LMO)
The image below identifies the LMO through its unique identifier, trade name and a link to this page of the BCH. Click on it to download a larger image on your computer. For help on how to use it go to the LMO quick-links page.
MOUSTICIDE™
EN
TMOF_yeast
No
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Person:Mr Mohd Alhafis RusdiTechnology Officer, RegulatoryD-3A-08, Plaza Mont' Kiara No. 2 Jalan Kiara, Mont' Kiara 50480 Kuala Lumpur MalaysiaKuala Lumpur,
50480, MalaysiaPhone: +603 6203 5531 / 6203 5532,Fax: +603 6206 5533,Email: al@entogenex.com,Website: http://entogenex.com/,Related OrganizationEntoGenex Industries Sdn. Bhd. ()Private sector (business and industry)D-3A-08, Plaza Mont' Kiara No. 2 Jalan Kiara, Mont' Kiara 50480 Kuala Lumpur MalaysiaKuala Lumpur,
50480, MalaysiaPhone: +603 6203 5531 / 6203 5532,Fax: +603 6206 5533,Email: al@entogenex.com,Website: http://entogenex.com/,
MOUSTICIDE™ is a biolarvicide that is, amongst other things, composed of heat inactivated Pichia pastoris KM71H strain transformed with pPICZ B plasmid containing gene sequences for expression of the Trypsin Modulating Oostatic Factor (TMOF) peptide.
Exposure of mosquito larvae to the TMOF peptide results in suppression of larval growth and development.
EN
Exposure of mosquito larvae to the TMOF peptide results in suppression of larval growth and development.
The term “Recipient organism” refers to an organism (either already modified or non-modified) that was subjected to genetic modification, whereas “Parental organisms” refers to those that were involved in cross breeding or cell fusion.
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BCH-ORGA-SCBD-106439-4 Organism Komagataella pastoris (Yeast)Fungi
EN
pPICZ B
EN
- Electroporation
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Some of these genetic elements may be present as fragments or truncated forms. Please see notes below, where applicable.
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BCH-GENE-SCBD-106440-1 Trypsin Modulating Oostatic Factor gene | Aedes aegypti (Yellow fever mosquito, AEDAE)Protein coding sequence | Changes in quality and/or metabolite content (Protein and amino acids)
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BCH-GENE-SCBD-106441-3 Alcohol oxidase 1 gene promoter | Komagataella pastoris (Yeast)Promoter
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BCH-GENE-SCBD-106442-1 Alcohol oxidase 1 gene terminator | Pichia pastoris (Yeast, PICPA)Terminator
The gene responsible for the modified trait(s) is a synthetic DNA sequence optimized for codon usage by Pichia pastoris to express the TMOF decapeptide as isolated from Aedes aegypti mosquito.
EN
EN
- Other (Biolarvicide )
EN
EN
- Trypsin Modulating Oostatic Factor (TMOF) (105403) Fact Sheet - US EPA [ English ]
- MOUSTICIDE™ [ English ]
- TMOF Biopesticide Registration Action Document - US EPA [ English ]
| Record type | Field | Record(s) | |
|---|---|---|---|
| Risk Assessment generated by a regulatory process | Living modified organism(s) | 2 | |
| Country's Decision or any other Communication | LMO identification | 2 | |
